Researchers design Laser-Induced Graphene sensors for sweat-based vitamin B6 tracking

Researchers from Hebei University of Technology, Tianjin University, Tianjin Tianzhong Yimai Technology Development Co., and The Pennsylvania State University have developed a wearable, regenerable, highly sensitive, and stable sweat sensor capable of near-real-time, accurate detection of water-soluble vitamin B6 in sweat. The platform, based on laser-induced graphene (LIG) nanocomposites, integrates molecularly imprinted polymers (MIPs) and Prussian blue (PBNP) redox probes to achieve exceptionally high sensitivity and stability in detecting ultralow concentrations of non-electroactive substances such as vitamins.

The sensor demonstrates a sensitivity of 39.95 μA log₁₀ (μM)⁻¹ mm⁻² and a limit of detection (LOD) of just 0.93 nM for vitamin B6, and can be readily adapted for glucose sensing, achieving a sensitivity of 19.33 μA log₁₀ (μM)⁻¹ mm⁻². When paired with a precision-designed microfluidic sweat sampling module, this integrated system enables continuous monitoring of trace biomarkers during exercise, offering promising applications in personalized nutrition and healthcare.

Read More Graphene-Info – Graphene industry portal